I use slic3r for my slicing needs these days, but when I was fooling around with cura a while back, these were the best profiles I found: https://github.com/cilynx/CuraProfiles.
Whether cura, slic3r, or anything else, your best bet will be to really learn the profile options and fine tune custom profiles specifically for your machine, filament, quality vs print-time, and complexity of design. For example, for large simple objects that don't need great finish, I have my machine laying down perimeters and solid fill layers at 140mm/s and 220 on the hot end -- right at the speed my extruder motor starts dropping steps due to pressure build-up. For intricate objects, I have slower and cooler profiles I've tuned empirically. I've also found that I'm constantly fine-tuning all of my profiles on each print, getting better and better quality in less and less time.