One RPi, multiple different printers. Is there a way to bind Serial port to profile and slicer-profile?

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Using a (1, one) raspberry pi with octoprint, with multiple different 3D printers.
Is there a way to bind: slicer(cura)-profile + Serial port, per profile?

Searching plugins, looking through settings in webgui. google...

Octopi 1.3.9
Raspberry Pi 3+
2 Ender 3
1 Ender 2
1 Creality CR-10 S5

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5 posts were merged into an existing topic: Multiple printers per Pi megathread

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