I'm not a beekeeper but I do love bees. Bee colonies are a small fraction of what they were perhaps seventy years ago. If honey bees go extinct then it's likely that we'll follow since they're responsible for pollenating most of our food crops. I personally would guess that the advent of cellphone technology is part of their undoing but other causes have been suggested.
The Varroa mite is one of those better-known threats. Once inside the brood chamber, the mites will devastate the colony.
To that end, I'm designing things for beekeepers so that they may be better armed against these mites.