State: Offline after error No more candidates to test, and no working port/baudrate combination detected

You already checked earlier in the thread with the lsusb command, there were no devices listed. That's a level below OctoPrint, if you deleted OctoPrint from the OS it wouldn't impact the results of lsusb. That's one of your key troubleshooting tools - if lsusb does not show the printer connected, then OctoPrint hasn't got a chance.

You could of course take a backup and reinstall OctoPrint/OctoPi, and test the same things, but I do believe coincidences can happen.

Replaced the board with a 4.2.7 and voila problem gone...

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