Yes, install the Desktop (see
sudo raspi-config to make it auto-boot into the Desktop.
Next, you'd need to create a line in a file called
chromium-browser --kiosk localhost and install Chromium on your Raspi with
sudo apt-get install -y chromium-browser.
If your LCD/TFT is in the correct orientation and you've installed everything as suggested, it should automatically boot into OctoPrint from a full-screen Chromium browser session. You may find that the touchscreen may or may not work; you'd then need to back up a step and calibrate that.