Did you correct the power feed issue from you PC to the printer?
What is it that you think needs to be cleaned up? The way OctoPrint is installed is really tight and there are no real external dependencies once installed correctly. Just about everything is installed in a single directory tree. Even on Windows, there is only one thing I can think of as a dependency and that is the serial driver for the USB to serial.
If you want a setup that "just works" your best bet is to buy a mini PC for $90 US. Make sure that it has a hard drive(SSD) and either install ubuntu desktop on it or make sure it comes with Ubuntu installed. The one linked to has all of that. If installing your self, I suggest Desktop because it will be more familiar and you will have an easier time mentally grappling with the fact that its not windows. You will also have a similar software update process as you have in windows. Although you get to avoid the auto reboot stuff .
Then install GIT, sudo apt install git (might already be installed)
Then follow the instructions for doing what I consider the easy install by Paul Paukstelis.
He has a link to a talk he did on his script in the main page readme.
Also make sure you block the 5v on the serial line. I do not like the tape method. Use a cable or other device to block it. There are a good number listed in the thread that @Ewald_Ikemann put in the other thread you had. I sell a power blocking cable, so its not hard to see that is what I prefer. Just make sure you do something here or you will likely continue to have issues.
If you do this, you will likely just need to do occasional OS updates and OctoPrint updates.
I will NEVER have Ubuntu crap installed on any of my machines - I've been there, dona that ... never again.
As I remember from my last attempt - I ran into problems with too old version of Phyton or something like that, so that's why I want to "Start all over" - and that's what I mean by dependencies.
Installing by clicking all the way ... that's my line of thinking