What is the problem?
Octoprint not connecting to printer anymore
What did you already try to solve it?
Reboot Octoprint and Printer
Change Budrate and Serial port
Change usb cable
Have you tried running in safe mode?
Yes
Did running in safe mode solve the problem?
No
Systeminfo Bundle
You can download this in OctoPrint's System Information dialog ... no bundle, no support!)
octoprint-systeminfo-20211029151048.zip (27.7 KB)
Additional information about your setup
OctoPrint version, OctoPi version, printer, firmware, browser, operating system, ... as much data as possible
OctoPrint Version 1.7.0, OctoPi Version 0.18.0, Creality Ender 3 v2, Firmvare Version 1.0.2, Chrome, Windows 10