Print jobs with long runtime abort "timeout while printing, trying to trigger response from printer"

What is the problem?

I have my Ender 3 V2 (with OctoPrint) for 3 weeks. Print jobs with short runtime are printed without problems, with larger jobs the USB connection between Raspi and Ender has broken down three times now - mostly after 9-10 hours.

Very annoying, because especially as a newbie I can not read so much from the log file.

What did you already try to solve it?

Restarted, checked the USB connection

Additional information about your setup

Systeminfo

browser.user_agent: Mozilla/5.0 (Windows NT 10.0; Win64; x64) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/87.0.4280.88 Safari/537.36
connectivity.connection_check: 8.8.8.8:53
connectivity.connection_ok: true
connectivity.enabled: true
connectivity.online: true
connectivity.resolution_check: octoprint.org
connectivity.resolution_ok: true
env.hardware.cores: 4
env.hardware.freq: 1500
env.hardware.ram: 1888698368
env.os.bits: 64
env.os.id: linux
env.os.platform: linux
env.plugins.pi_support.model: Raspberry Pi 4 Model B Rev 1.2
env.plugins.pi_support.octopi_version: 0.18.0
env.plugins.pi_support.throttle_state: 0x0
env.python.pip: 20.2.4
env.python.version: 3.7.3
env.python.virtualenv: true
octoprint.safe_mode: false
octoprint.version: 1.5.2
printer.firmware: Marlin bugfix-2.0.x (Dec 9 2020

Logfile

2020-12-23 14:35:02,960 - octoprint.plugins.preheat - INFO - Preheating tool0 to 215.0.
2020-12-23 14:35:02,963 - octoprint.plugins.preheat - INFO - Preheating bed to 40.0.
2020-12-23 14:35:16,262 - octoprint.util.comm - INFO - Starting job on behalf of user KaPe
2020-12-23 14:35:16,275 - octoprint.util.comm - INFO - Changing monitoring state from "Operational" to "Starting"
2020-12-23 14:35:16,283 - octoprint.printer.standard.job - INFO - Print job started - origin: local, path: Ender3v2_Feet_.gcode, owner: KaPe, user: KaPe
2020-12-23 14:35:16,407 - octoprint.plugins.DisplayLayerProgress - INFO - Printing started. Detailed progress started.{'name': 'Ender3v2_Feet_.gcode', 'path': 'Ender3v2_Feet_.gcode', 'origin': 'local', 'size': 16475111, 'owner': 'KaPe', 'user': 'KaPe'}
2020-12-23 14:35:16,421 - octoprint.util.comm - INFO - M110 detected, setting current line number to 0
2020-12-23 14:35:16,442 - octoprint.util.comm - INFO - Changing monitoring state from "Starting" to "Printing"
2020-12-23 21:59:30,632 - octoprint.plugins.softwareupdate - INFO - Fetching check overlays from https://plugins.octoprint.org/update_check_overlay.json
2020-12-23 21:59:33,367 - octoprint.server.util.sockjs - INFO - User KaPe logged in on the socket from client ::ffff:192.168.188.151
2020-12-23 21:59:34,648 - octoprint.plugins.announcements - INFO - Loaded channel _important from Important OctoPrint Announcements in 0.085s
2020-12-23 21:59:34,836 - octoprint.plugins.announcements - INFO - Loaded channel _releases from OctoPrint Release Announcements in 0.082s
2020-12-23 21:59:34,954 - octoprint.plugins.announcements - INFO - Loaded channel _blog from OctoBlog in 0.088s
2020-12-23 21:59:35,071 - octoprint.plugins.announcements - INFO - Loaded channel _plugins from OctoPrint Plugin Repository in 0.088s
2020-12-23 21:59:35,204 - octoprint.plugins.announcements - INFO - Loaded channel _octopi from OctoPi Announcements in 0.087s
2020-12-23 21:59:35,385 - octoprint.plugins.pluginmanager - INFO - Loaded plugin notices data from https://plugins.octoprint.org/notices.json
2020-12-23 21:59:35,840 - octoprint.plugins.softwareupdate - INFO - Saved version cache to disk
2020-12-23 22:02:00,030 - octoprint.server.util.sockjs - INFO - Client connection closed: ::ffff:192.168.188.151
2020-12-23 22:10:31,374 - octoprint.server.heartbeat - INFO - Server heartbeat <3
2020-12-23 22:10:38,387 - octoprint.plugins.tracking - INFO - Sent tracking event ping, payload: {'octoprint_uptime': 114308}
2020-12-23 22:25:31,375 - octoprint.server.heartbeat - INFO - Server heartbeat <3
2020-12-23 22:25:38,424 - octoprint.plugins.tracking - INFO - Sent tracking event ping, payload: {'octoprint_uptime': 115208}
2020-12-23 22:40:31,376 - octoprint.server.heartbeat - INFO - Server heartbeat <3
2020-12-23 22:40:38,406 - octoprint.plugins.tracking - INFO - Sent tracking event ping, payload: {'octoprint_uptime': 116108}
2020-12-23 22:55:31,377 - octoprint.server.heartbeat - INFO - Server heartbeat <3
2020-12-23 22:55:38,416 - octoprint.plugins.tracking - INFO - Sent tracking event ping, payload: {'octoprint_uptime': 117008}
2020-12-23 23:00:16,144 - octoprint.server.util.flask - INFO - Passively logging in user KaPe from ::ffff:192.168.188.151
2020-12-23 23:00:16,145 - octoprint.access.users - INFO - Logged in user: KaPe
2020-12-23 23:10:31,379 - octoprint.server.heartbeat - INFO - Server heartbeat <3
2020-12-23 23:10:38,410 - octoprint.plugins.tracking - INFO - Sent tracking event ping, payload: {'octoprint_uptime': 117908}
2020-12-23 23:25:31,380 - octoprint.server.heartbeat - INFO - Server heartbeat <3
2020-12-23 23:25:38,447 - octoprint.plugins.tracking - INFO - Sent tracking event ping, payload: {'octoprint_uptime': 118808}
2020-12-23 23:40:31,381 - octoprint.server.heartbeat - INFO - Server heartbeat <3
2020-12-23 23:40:38,392 - octoprint.plugins.tracking - INFO - Sent tracking event ping, payload: {'octoprint_uptime': 119708}
2020-12-23 23:55:31,382 - octoprint.server.heartbeat - INFO - Server heartbeat <3
2020-12-23 23:55:38,421 - octoprint.plugins.tracking - INFO - Sent tracking event ping, payload: {'octoprint_uptime': 120608}
2020-12-24 00:10:31,383 - octoprint.server.heartbeat - INFO - Server heartbeat <3
2020-12-24 00:10:38,414 - octoprint.plugins.tracking - INFO - Sent tracking event ping, payload: {'octoprint_uptime': 121508}
2020-12-24 00:25:31,384 - octoprint.server.heartbeat - INFO - Server heartbeat <3
2020-12-24 00:25:38,418 - octoprint.plugins.tracking - INFO - Sent tracking event ping, payload: {'octoprint_uptime': 122408}
2020-12-24 00:40:31,385 - octoprint.server.heartbeat - INFO - Server heartbeat <3
2020-12-24 00:40:38,424 - octoprint.plugins.tracking - INFO - Sent tracking event ping, payload: {'octoprint_uptime': 123308}
2020-12-24 00:46:57,995 - octoprint.util.comm - INFO - Communication timeout while printing, trying to trigger response from printer.
2020-12-24 00:47:01,002 - octoprint.util.comm - INFO - Communication timeout while printing, trying to trigger response from printer.
2020-12-24 00:47:04,007 - octoprint.util.comm - INFO - Communication timeout while printing, trying to trigger response from printer.
2020-12-24 00:47:07,013 - octoprint.util.comm - INFO - Communication timeout while printing, trying to trigger response from printer.
2020-12-24 00:47:10,019 - octoprint.util.comm - INFO - Communication timeout while printing, trying to trigger response from printer.
2020-12-24 00:47:13,024 - octoprint.util.comm - INFO - No response from printer after 6 consecutive communication timeouts, considering it dead.
2020-12-24 00:47:13,084 - octoprint.util.comm - INFO - Changing monitoring state from "Printing" to "Offline (Error: Too many consecutive timeouts, printer still connected and alive?)"
2020-12-24 00:47:13,157 - octoprint.plugins.action_command_notification - INFO - Notifications cleared
2020-12-24 00:47:13,200 - octoprint.plugins.filamentmanager - INFO - Filament used: 18322.59012000306 mm (tool0)
2020-12-24 00:47:13,227 - octoprint.plugins.tracking - INFO - Sent tracking event commerror_timeout, payload: {'commerror_text': 'Too many consecutive timeouts, printer still connected and alive?'}
2020-12-24 00:47:13,303 - octoprint.plugins.DisplayLayerProgress - INFO - Printing stopped. Detailed progress stopped.
2020-12-24 00:47:13,439 - octoprint.plugins.tracking - INFO - Sent tracking event print_failed, payload: {'origin': 'local', 'file': '972b6b48f45fc375175958d7c58167e575edf1dd', 'elapsed': 36716, 'reason': 'error', 'commerror_text': 'Too many consecutive timeouts, printer still connected and alive?'}
2020-12-24 00:55:31,386 - octoprint.server.heartbeat - INFO - Server heartbeat <3
2020-12-24 00:55:38,379 - octoprint.plugins.tracking - INFO - Sent tracking event ping, payload: {'octoprint_uptime': 124208}
2020-12-24 01:10:31,387 - octoprint.server.heartbeat - INFO - Server heartbeat <3
2020-12-24 01:10:38,412 - octoprint.plugins.tracking - INFO - Sent tracking event ping, payload: {'octoprint_uptime': 125108}
2020-12-24 01:25:31,388 - octoprint.server.heartbeat - INFO - Server heartbeat <3
2020-12-24 01:25:38,421 - octoprint.plugins.tracking - INFO - Sent tracking event ping, payload: {'octoprint_uptime': 126008}
2020-12-24 01:40:31,390 - octoprint.server.heartbeat - INFO - Server heartbeat <3
2020-12-24 01:40:38,432 - octoprint.plugins.tracking - INFO - Sent tracking event ping, payload: {'octoprint_uptime': 126908}
2020-12-24 01:55:31,391 - octoprint.server.heartbeat - INFO - Server heartbeat <3
2020-12-24 01:55:38,436 - octoprint.plugins.tracking - INFO - Sent tracking event ping, payload: {'octoprint_uptime': 127808}
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