Printer does not show up on OSX

What is the problem?
I got octoprint running on my MacBook Pro, only Problem I got is octoprint does not recognize the printer. Only if I restart the mac, it works until I turn of the printer, after that the printer shows up in the usb section of the mac info, but Orctoptint does not see the serial. Installalled the newest drivers too. It a CR 10S Pro and shows up as FT232R USB UART.
What did you already try to solve it?
I installed the newes drivers.
Additional information about your setup (OctoPrint version, OctoPi version, printer, firmware, octoprint.log, serial.log or output on terminal tab, ...)