My environment hasn't changed, apart from updates, for the last three years. Yesterday my printer (Creality CR-10 S5), stopped connecting to Octopi. Everything seems to be happy, but it just won't connect.
What did you already try to solve it?
Rebooted the printer & Octopi server
I tried connecting to other USB ports on the Pi
Have you tried running in safe mode?
Yes
Did running in safe mode solve the problem?
No
Systeminfo Bundle
You can download this in OctoPrint's System Information dialog ... no bundle, no support!)
I switched it to AUTO and it connected at 115200
Jeez, boy do I feel like an idiot. I have no clue how that would have changed though, but whatever, thanks for pointing that out.