What is the problem?
I am looking to set up octoprint under fedora 29 linux
What did you already try to solve it?
Not much; I am looking to see if there is a rpm available.
Additional information about your setup (OctoPrint version, OctoPi version, printer, firmware, octoprint.log, serial.log or output on terminal tab, ...)
I have 3 printers; one homemade prusa I2, a Geeetech prusa I3 and a Creality CR-10
It isn't an RPM, but here's the howto:
Yes, that's Raspbian, but it's roughly the same install steps.
sudo yum -y install python python-pip virtualenv
git clone https://github.com/foosel/OctoPrint.git && cd OctoPrint
virtualenv -p /usr/bin/python2.7 venv
./venv/bin/python setup.py install
./venv/bin/octoprint
should do it on fedora 30... at least it does for me 
Wouldn't you need to source venv/bin/activate and then python setup.py install and octoprint serve (instead of the last two lines)?
I think it is also possible. I installed it ajar to the official installation from source.
When OctoPrint's own Software Update plugin fires off, it may or may not work unless you're running within the confines of the virtual environment. There may be a way to set command line arguments so that Python and pip know which one is meant to run, though.