When I'm booting Octoprint, the first print runs with the wrong temperatures. I've only one profile with PLA (tool 200°C and bed 60°C). When I set the profile in "Cible", values are correct. When I run a gcode file containing the exact same values (1) the tool sets its temperature to 60°C and Bed to 100°C (may be the max of the bed). So I stop the job because values are wrong. I set once again "Cible" to my PLA profile, values are correct. I run once again the same code and values on tool and bed are then ok. It happens all the time after the first Octoprint boot.
Instead of disabling one plugin at a time, you can use the binary search method where you disable half of the plugins and test. If it doesn't fail, the culprit is in the half you disabled. If it still fails, the culprit is in the half still enabled. Repeat by disabling or enabling half of the plugins in the failing half. With 8 plugins, you get to the result in 3 steps and with 16 plugins, 4 steps.
Once you solve the original issue, I believe the start gcode for the printer doesn't optimize the heating of the bed and the nozzle. There is very little point in M140 followed immediately with a M190 (the M105 in the middle is just a temperature report). Move the M104 before the M190 and the bed and the nozzle will start heating at the same time.
. After disabling it, no more problems.